A3: SFB-relevante Publikationen

Projektleitung: Prof. Dr. M. Brand

• Scholpp, S. , Brand, M. and Lumsden, A. (2006). Hedgehog signalling from the Zona Limitans Intrathalamica orchestrates differentiation of the zebrafish diencephalon. Development, in press.
• Kaslin, J., Ganz, J., and Brand, M. (2006). Proliferation, neurogenesis and regeneration in the non-mammalian vertebrate brain. Philos Trans R Soc Lond B Biol Sci, Stem Cell Issue, in press.
• Grandel, H., Kaslin, J., Ganz, J., Wenzel, I., and Brand, M. (2006). Neural stem cells and neurogenesis in the adult zebrafish brain: origin, proliferation dynamics, migration and cell fate. Developmental Biology, 295(1):263-277.
• Rhinn, M., Picker, A., and Brand, M. (2006). Global and local mechanisms of forebrain and midbrain patterning. Curr Opin Neurobiology 16, 1-8.
• Langenberg, T., Dracz, T., Oates, A.C., Heisenberg, C.P. and Brand, M. (2006). Analysis and visualization of cell movement in the developing zebrafish brain. Developmental Dynamics, 235(4); 928-933.
• Rhinn, M., Lun, K., Luz, M., Werner, M., Brand, M. (2005). Positioning of the midbrain-hindbrain boundary organizer through global posteriorisation of the neuroectoderm mediated by Wnt8 signaling. Development 132, 1261-1272.
• Picker, A. and Brand, M. (2005). Fgf-signals from a novel signaling center determine axial patterning of the prospective neural retina. Development 132, 4951-4962.
• Langenberg T, Brand M. (2005). Lineage restriction maintains a stable organizer cell population at the zebrafish midbrain-hindbrain boundary. Development 132, 3209-3216.
• Scholpp, S. and Brand, M. (2004). Endocytosis controls spreading and effective signaling range of Fgf8. Current Biology 14, 1834-1841.
• Rhinn, M., Lun, K., Werner, M., Simeone, A. and Brand, M. (2004). Isolation and expression of the homeobox gene Gbx1 during mouse development. Developmental Dynamics 229, 334-339.
• Scholpp, S., Groth, C., Lardelli, M., and Brand, M. (2004). Fgfr1 mediates Fgf8 signalling at the midbrain-hindbrain boundary of zebrafish embryos. Development, Genes and Evolution 214, 285-295.
• Raible, F. and Brand, M. (2004). Divide et Impera – The Midbrain-Hindbrain Boundary and Its Organizer. Trends in Neurosciences 27, 727-735.
• Langenberg, T., Brand, M. and Cooper, M. (2003). Imaging brain development and organogenesis in zebrafish using immobilized embryonic explants. Developmental Dynamics 228, 464-474.
• Jászai, J., Reifers, F., Picker, A., Langenberg, T. and Brand, M. (2003). Isthmus-to-midbrain transformation in the absence of midbrain-hindbrain organizer activity. Development 130, 6611-6623.
• Scholpp, S., Lohs, C. and Brand, M. (2003). Engrailed and Fgf8 act synergistically to maintain the boundary between forebrain and midbrain. Development 130, 4881-4893.
• Scholpp, S. and Brand, M. (2003). Integrity of the midbrain region is required to maintain a stable posterior forebrain boundary in zebrafish no isthmus/pax2.1 mutants. Developmental Dynamics 228, 313-322.
• Rhinn, M., Lun, K., Werner, M., Amores, A., Yan, Y. L., Postlethwait, J. and Brand, M. (2003). Cloning, expression and relationship of zebrafish gbx1 and gbx2 genes to Fgf signaling during early brain development. Mechanisms of Development 120, 919-936.
• Léger, S. and Brand, M. (2002). Fgf8 and Fgf3 are required for zebrafish ear placode induction, maintenance and inner ear patterning. Mechanisms of Development 119, 91-108.
• Picker, A., Scholpp, S., Böhli, H., Takeda, H. and Brand, M. (2002). A novel positive transcriptional feedback loop in midbrain-hindbrain boundary development is revealed through analysis of the zebrafish pax2.1 promoter in transgenic lines. Development 129, 3227-3239.
• Reim, G. and Brand, M. (2002). spiel-ohne-grenzen/pou2 mediates regional competence to respond to Fgf8 during zebrafish early neural development. Development 129, 917-933.
• Rhinn, M. and Brand, M. (2001). The midbrain-hindbrain organizer. Current Opinion in Neurobiology 11, 34-42.
• Reifers, F., Walsh, E. C., Léger, S., Stainier, D. Y. R., and Brand, M. (2000). Induction and differentiation of the zebrafish heart requires Fibroblast Growth Factor 8 (Fgf8/acerebellar). Development 127, 225-235.
• Picker, A., Brennan, C., Reifers, F., Böhli, H., Holder, N., and Brand, M. (1999). Requirement for zebrafish acerebellar/FGF8 in midbrain polarization, mapping and confinement of the retinotectal projection.
• Reifers, F., Böhli, H., Walsh, E. C., Crossley, P. H., Stainier, D. Y. R., and Brand, M. (1998). Fgf8 is mutated in zebrafish acerebellar mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 125, 2381-2395. Development 126, 2967-2978.
• Brand, M., Heisenberg, C.-P., Warga, R. M., Pelegri, F., Karlstrom, R. O., Beuchle, D., Picker, A., Jiang, Y.-J., Furutani-Seiki, M., van Eeden, F. J. M., et al. (1996). Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. Development 123, 129-142.
• Brand, M., Heisenberg, C.-P., Jiang, Y.-J., Beuchle, D., Lun, K., van Eeden, F. J. M., Furutani-Seiki, M., Granato, M., Haffter, P., Hammerschmidt, M., et al. (1996). Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain. Development 123, 179-190.