A6: SFB-relevante Publikationen

Projektleitung: Prof. Dr. S. Bornstein / Dr. M. Ehrhart-Bornstein

• Bornstein SR, Engeland WC, Ehrhart-Bornstein M, Herman JP: Dissociation of ACTH and Glucocorticoids. Trends in Endocrinology and Metabolism (2008) in press

• Ziegler CG, Sicard F, Lattke P, Bornstein SR, Ehrhart-Bornstein M, Krug A: Dehydroepiandrosterone (DHEA) induces a neuroendocrine phenotype in nerve growth factor (NGF)-stimulated chromaffin pheochromocytoma PC12 cells. Endocrinology. First published ahead of print September 20, 2007 as doi:10.1210/en.2007-0645

• Sicard F, Ehrhart-Bornstein M, Corbeil D, Sperber S, Krug AW, Ziegler CG, Rettori V, McCann SM, Bornstein SR: Growth factors, DHEA and DHEAS regulate chromaffin cells proliferation in an age-dependent manner. Proc Natl Acad Sci U S A (2007) 104: 2007-2012
  
• Ziegler CG, Sicard F, Sperber S, Ehrhart-Bornstein M, Bornstein SR, Krug AW: DHEA reduces NGF-mediated cell survival in serum-deprived PC12 cells. Ann N Y Acad Sci (2006) 1073:306-311
• Zacharowski K, Zacharowski PA, Koch A, Baban A, Tran N, Berkels R, Papewalis C, Schulze-Osthoff K, Knuefermann P, Zahringer U, Schumann RR, Rettori V, McCann SM, Bornstein SR: Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic inflammatory response syndrome. Proc Natl Acad Sci U S A (2006) 103:6392-6397
• Bornstein SR, Yoshida-Hiroi M, Sotiriou S, Levine M, Hartwig HG, Nussbaum RL, Eisenhofer G: Impaired adrenal catecholamine system function in mice with deficiency of the ascorbic acid transporter (SVCT2). FASEB J (2003) 17:1928-1930
• Beaujean D, Rosenbaum C, Muller HW, Willemsen JJ, Lenders J, Bornstein SR: Combinatorial code of growth factors and neuropeptides define neuroendocrine differentiation in PC12 cells. Exp Neurol (2003) 184:348-358
• Ehrhart-Bornstein M, Lamounier-Zepter V, Schraven A, Langenbach J, Willenberg HS, Barthel A, Hauner H, McCann SM, Scherbaum WA, Bornstein SR: Human adipocytes secrete mineralocorticoid releasing factors. Proc Natl Acad Sci U S A (2003) 100:14211-14216
• Merke DP, Bornstein SR, Avila NA, Chrousos GP: Future directions in the study and management of congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Ann Intern Med (2002) 136:320-334
• Galon J, Franchimont D, Hiroi N, Frey G, Böttner A, Ehrhart-Bornstein M, O'Shea JJ, Chrousos GP, Bornstein SR: Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells. FASEB J (2002) 16:61-71
• Alesci S, Ramsey WJ, Bornstein SR, Chrousos GP, Hornsby PJ, Benvenga S, Trimarchi F, Ehrhart-Bornstein M: Adenoviral vectors can impair adrenocortical steroidogenesis: clinical implications for natural infections and gene therapy. Proc Natl Acad Sci U S A (2002) 99:7484-7489
• Merke DP, Chrousos GP, Eisenhofer G, Weise M, Keil MF, Rogol AD, van Wyk JJ, Bornstein SR: Adrenomedullary dysplasia and hypofunction in patients with classic 21-hydroxylase defiency. N Engl J Med (2000) 343:1362-1368
• Bornstein SR, Tian H, Haidan A, Böttner A, Hiroi N, Eisenhofer G, McCann SM, Chrousos GP, Roffler-Tarlov S: Deletion of tyrosine hydroxylase gene reveals functional interdependence of adrenocortical and chromaffin cell system in vivo. Proc Natl Acad Sci U S A (2000) 97:14742-14747
• Bornstein SR, Tajima T, Eisenhofer G, Haidan A, Aguilera G: Adrenomedullary function is severely impaired in 21-hydroxylase-deficient mice. FASEB J (1999) 13:1185-1194
• Willenberg HS, Stratakis CA, Marx C, Ehrhart-Bornstein M, Chrousos GP, Bornstein SR Aberrant interleukin-1 receptor in a cortisol-secreting adrenal adenoma causing Cushing's syndrome. N Engl J Med (1998) 339:27-31
• Haidan A, Bornstein SR, Glasow A, Uhlmann K, Lübke C, Ehrhart-Bornstein M: Basal steroidogenic activity of adrenocortical cells is increased tenfold by co-culture with chromaffin cells. Endocrinology (1998) 139:772-780
• Ehrhart-Bornstein M, Hinson JP, Bornstein SR, Scherbaum WA, Vinson GP: Intraadrenal interactions in the regulation of adrenocortical steroidogenesis. Endocr Rev (1998) 19:101-143
• Bornstein SR, Ehrhart-Bornstein M, Scherbaum WA, Pfeiffer EF, Holst JJ: Effects of splanchnic nerve stimulation on the adrenal cortex may be mediated by chromaffin cells in a paracrine manner. Endocrinology (1990) 127:900-906